Mannosulfan

Mannosulfan
Clinical data
Synonyms	[(2R,3S,4S,5R)-3,4-dihydroxy-2,5,6-tris(methylsulfonyloxy)hexyl] methanesulfonate
ATC code	L01AB03 (WHO) ;
Identifiers
	IUPAC name 1,2,5,6-Tetrakis-O-(methylsulfonyl)-D-mannitol;
PubChem CID	24140;
ChemSpider	16736959;
UNII	135FQ40L36;
Chemical and physical data
Formula	C10H22O14S4
Molar mass	494.53 g/mol
3D model (JSmol)	Interactive image;
	SMILES CS(=O)(=O)OC[C@H]([C@H]([C@@H]([C@@H](COS(=O)(=O)C)OS(=O)(=O)C)O)O)OS(=O)(=O)C;
	InChI InChI=1S/C10H22O14S4/c1-25(13,14)21-5-7(23-27(3,17)18)9(11)10(12)8(24-28(4,19)20)6-22-26(2,15)16/h7-12H,5-6H2,1-4H3/t7-,8-,9-,10-/m1/s1; Key:UUVIQYKKKBJYJT-ZYUZMQFOSA-N;
(verify)

Mannosulfan (INN) is an alkylating agent with potential for treatment of cancer. It is not approved by the United States FDA for cancer treatment. Research suggests it is less toxic than the alkyl sulfonate Busulfan.^[1]

References

↑ Jeswani, Gunjan; Paul, Swarnali D (2017). "Recent Advances in the Delivery of Chemotherapeutic Agents". Nano- and Microscale Drug Delivery Systems. pp. 281–98. doi:10.1016/B978-0-323-52727-9.00015-7. ISBN 978-0-323-52727-9.

External links

Media related to Mannosulfan at Wikimedia Commons

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[1] Jeswani, Gunjan; Paul, Swarnali D (2017). "Recent Advances in the Delivery of Chemotherapeutic Agents". Nano- and Microscale Drug Delivery Systems. pp. 281–98. doi:10.1016/B978-0-323-52727-9.00015-7. ISBN 978-0-323-52727-9.