Zinc transporter ZIP10

SLC39A10
Identifiers
Aliases	SLC39A10, LZT-Hs2, solute carrier family 39 member 10
External IDs	OMIM: 608733 MGI: 1914515 HomoloGene: 34076 GeneCards: SLC39A10
Gene location (Human)
Chr.	Chromosome 2 (human)[1]
End	195,737,702 bp[1]
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)[2]
End	46,892,852 bp[2]
Gene ontology
Molecular function	• metal ion transmembrane transporter activity; • zinc ion transmembrane transporter activity;
Cellular component	• integral component of membrane; • cell membrane; • membrane; • integral component of plasma membrane;
Biological process	• metal ion transport; • negative regulation of B cell apoptotic process; • positive regulation of protein tyrosine phosphatase activity; • zinc II ion transport; • ion transport; • positive regulation of B cell proliferation; • transmembrane transport; • cellular zinc ion homeostasis; • positive regulation of B cell receptor signaling pathway; • zinc II ion transmembrane import;
	Sources:Amigo / QuickGO
Orthologs
	57181
	227059
	ENSG00000196950
	ENSMUSG00000025986
	Q9ULF5
	Q6P5F6
	NM_001127257; NM_020342
	NM_172653; NM_001356416; NM_001356417
	NP_001120729; NP_065075
	NP_766241; NP_001343345; NP_001343346
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc transporter ZIP10, also known as solute carrier family 39 member 10, is a protein that in humans is encoded by the SLC39A10 gene.[5] ZIP10 belongs to a subfamily of proteins that show structural characteristics of zinc transporters, and have 14 members in the human genome: ZIP1, ZIP2, ZIP3, ZIP4, ZIP5, ZIP6, ZIP7, ZIP8, ZIP9, ZIP10, ZIP11, ZIP12, ZIP13 and ZIP14.[5][6]

References

GRCh38: Ensembl release 89: ENSG00000196950 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000025986 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Taylor KM, Morgan HE, Smart K, Zahari NM, Pumford S, Ellis IO, Robertson JF, Nicholson RI (Jul–Aug 2007). "The emerging role of the LIV-1 subfamily of zinc transporters in breast cancer". Mol Med. 13 (7–8): 396–406. doi:10.2119/2007-00040.Taylor. PMC 1936980. PMID 17673939.
Eide DJ (February 2004). "The SLC39 family of metal ion transporters". Pflügers Arch. 447 (5): 796–800. doi:10.1007/s00424-003-1074-3. PMID 12748861.

Zinc transporter ZIP10

References

Further reading