SLC2A7

Solute carrier family 2, facilitated glucose transporter member 7 also known as glucose transporter 7 (GLUT7) is a protein that in humans is encoded by the SLC2A7 gene.[5][6]

SLC2A7
Identifiers
AliasesSLC2A7, GLUT7, solute carrier family 2 member 7, GLUT-7, hGLUT7
External IDsOMIM: 610371 MGI: 3650865 HomoloGene: 72470 GeneCards: SLC2A7
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p36.23Start9,003,300 bp[1]
End9,026,345 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

155184

435818

Ensembl

ENSG00000197241

ENSMUSG00000062064

UniProt

Q6PXP3

P0C6A1

RefSeq (mRNA)

NM_207420

NM_001085529
NM_001368869

RefSeq (protein)

NP_997303

NP_001078998
NP_001355798

Location (UCSC)Chr 1: 9 – 9.03 MbChr 4: 150.15 – 150.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SLC2A7 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion.[6] This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues.[7]

See also

References
  1. GRCh38: Ensembl release 89: ENSG00000197241 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000062064 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: solute carrier family 2 (facilitated glucose transporter)".
  6. Li Q, Manolescu A, Ritzel M, Yao S, Slugoski M, Young JD, Chen XZ, Cheeseman CI (July 2004). "Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine". Am. J. Physiol. Gastrointest. Liver Physiol. 287 (1): G236–42. doi:10.1152/ajpgi.00396.2003. PMID 15033637.
  7. Joost HG, Thorens B (2001). "The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review)". Mol. Membr. Biol. 18 (4): 247–56. doi:10.1080/09687680110090456. PMID 11780753.

Further reading
  • Manolescu A, Salas-Burgos AM, Fischbarg J, Cheeseman CI (2005). "Identification of a hydrophobic residue as a key determinant of fructose transport by the facilitative hexose transporter SLC2A7 (GLUT7)". J. Biol. Chem. 280 (52): 42978–83. doi:10.1074/jbc.M508678200. PMID 16186102.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.