SLC23A2

Solute carrier family 23 member 2 is a protein that in humans is encoded by the SLC23A2 gene.[5][6][7]

SLC23A2
Identifiers
AliasesSLC23A2, NBTL1, SLC23A1, SVCT2, YSPL2, hSVCT2, solute carrier family 23 member 2
External IDsOMIM: 603791 MGI: 1859682 HomoloGene: 68440 GeneCards: SLC23A2
Gene location (Human)
Chr.Chromosome 20 (human)[1]
Band20p13Start4,852,356 bp[1]
End5,010,293 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

9962

54338

Ensembl

ENSG00000089057

ENSMUSG00000027340

UniProt

Q9UGH3

Q9EPR4

RefSeq (mRNA)

NM_005116
NM_203327

NM_018824
NM_001355430
NM_001355431

RefSeq (protein)

NP_005107
NP_976072

NP_061294
NP_001342359
NP_001342360

Location (UCSC)Chr 20: 4.85 – 5.01 MbChr 2: 132.05 – 132.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two required transporters and the encoded protein accounts for tissue-specific uptake of vitamin C. Previously, this gene had an official symbol of SLC23A1.[7]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000089057 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000027340 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Faaland CA, Race JE, Ricken G, Warner FJ, Williams WJ, Holtzman EJ (Dec 1998). "Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase transporters". Biochim Biophys Acta. 1442 (2–3): 353–60. doi:10.1016/S0167-4781(98)00151-1. PMID 9804989.
  6. Tsukaguchi H, Tokui T, Mackenzie B, Berger UV, Chen XZ, Wang Y, Brubaker RF, Hediger MA (Jun 1999). "A family of mammalian Na+-dependent L-ascorbic acid transporters". Nature. 399 (6731): 70–5. doi:10.1038/19986. PMID 10331392.
  7. "Entrez Gene: SLC23A2 solute carrier family 23 (nucleobase transporters), member 2".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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