MR-2096

MR-2096 is an opioid analgesic drug related to oxymorphone. It has an unusual chiral tetrahydrofuran-2-ylmethyl substitution on the nitrogen which determines the character of effects, with the (R) enantiomer MR-2096 being an opioid agonist, while the (S) enantiomer MR-2097 has similarly potent opioid antagonist effects. This mix of activities has made these two enantiomers useful for characterising the binding site of the mu opioid receptor.[1]

MR-2096
Identifiers
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC21H25NO5
Molar mass371.433 g·mol−1
3D model (JSmol)

See also

References

  1. Ramabadran K, Jen MF (April 1985). "Opioid agonist and antagonist properties of diastereoisomeric N-tetrahydronoroxymorphones in mice". Archives Internationales de Pharmacodynamie et de Therapie. 274 (2): 180–8. PMID 4040738.
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