Clocinnamox

Clocinnamox is a selective, irreversible μ-opioid receptor antagonist.[1]

Clocinnamox
Names
IUPAC name
(E)-N-[(4R,4aS,7aR,12bR)-3-(Cyclopropylmethyl)-9-hydroxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-3-(4-chlorophenyl)prop-2-enamide
Other names
Chlorocinnamoylaminodihydronormorphinone
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
Properties
C29H29ClN2O4
Molar mass 505.01 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. Filho, CB; Del Fabbro, L; De Gomes, MG; Goes, AT; Souza, LC; Boeira, SP; Jesse, CR (2013). "Kappa-opioid receptors mediate the antidepressant-like activity of hesperidin in the mouse forced swimming test". European Journal of Pharmacology. 698 (1–3): 286–91. doi:10.1016/j.ejphar.2012.11.003. PMID 23178563.


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