Equilibrative nucleoside transporter
The equilibrative nucleoside transporter (ENT) family, also known as SLC29, is a group of plasmalemmal transport proteins which transport nucleoside substrates like adenosine into cells.[1] There are four known ENTs, designated ENT1, ENT2, ENT3, and ENT4.[1][2] ENTs are blocked by adenosine reuptake inhibitors like dipyridamole and dilazep, drugs used clinically for their vasodilatory properties.[2][3]
References
- Baldwin SA, Beal PR, Yao SY, King AE, Cass CE, Young JD (Feb 2004). "The equilibrative nucleoside transporter family, SLC29". Pflügers Archiv. 447 (5): 735–43. doi:10.1007/s00424-003-1103-2. PMID 12838422.
- Molina-Arcas M, Casado FJ, Pastor-Anglada M (Oct 2009). "Nucleoside transporter proteins". Current Vascular Pharmacology. 7 (4): 426–34. doi:10.2174/157016109789043892. PMID 19485885.
- Noji T, Karasawa A, Kusaka H (Jul 2004). "Adenosine uptake inhibitors". European Journal of Pharmacology. 495 (1): 1–16. doi:10.1016/j.ejphar.2004.05.003. PMID 15219815.
Further reading
- Molina-Arcas M, Casado FJ, Pastor-Anglada M (Oct 2009). "Nucleoside transporter proteins". Current Vascular Pharmacology. 7 (4): 426–34. doi:10.2174/157016109789043892. PMID 19485885.
- Baldwin SA, Beal PR, Yao SY, King AE, Cass CE, Young JD (Feb 2004). "The equilibrative nucleoside transporter family, SLC29". Pflügers Archiv. 447 (5): 735–43. doi:10.1007/s00424-003-1103-2. PMID 12838422.
- Molina-Arcas M, Trigueros-Motos L, Casado FJ, Pastor-Anglada M (Jun 2008). "Physiological and pharmacological roles of nucleoside transporter proteins". Nucleosides, Nucleotides & Nucleic Acids. 27 (6): 769–78. doi:10.1080/15257770802145819. PMID 18600539.
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