2-Fluoroethanol

2-Fluoroethanol is the chemical compound with the formula CH2FCH2OH and the simplest fluorohydrin. This colorless liquid is one of the simplest stable fluorinated alcohols. It was developed for use as a rodenticide, insecticide, and acaricide. Owing to its easy oxidation to fluoroacetic acid, fluoroethanol is highly toxic (LD50 = 10 mg/kg). The related difluoro- and trifluoroethanols are far less dangerous.[4]

2-Fluoroethanol[1]
Names
Other names
Ethylene fluorohydrine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.006.128
UNII
Properties
C2H5FO
Molar mass 64.059 g·mol−1
Density 1.1040 g cm−3[1]
Melting point −26.3 °C (−15.3 °F; 246.8 K)[1]
Boiling point 103.5 °C (218.3 °F; 376.6 K)[1]
miscible[1]
Vapor pressure 19 mbar (15 °C)[1]
Acidity (pKa) 14.42[2]
Hazards
R-phrases (outdated) R10 R26/27/28
S-phrases (outdated) S36/37/39 S45
Lethal dose or concentration (LD, LC):
5 mg·kg−1(Rat, oral)[3]
1.10 g·m−3·10min−1 (LC50, Mouse, Inhalation)[3]
0.20 g·m−3·10min−1 (LC50, Rat, Inhalation)[3]
Related compounds
Other anions
2-Chloroethanol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

See also

References

  1. Record of CAS RN 371-62-0 in the GESTIS Substance Database of the Institute for Occupational Safety and Health, accessed on 18. February 2010.
  2. 2-Fluoroethanol in the ChemIDplus database
  3. MSDS from AlfaAesar
  4. Günter Siegemund, Werner Schwertfeger, Andrew Feiring, Bruce Smart, Fred Behr, Herward Vogel, Blaine McKusick “Fluorine Compounds, Organic” in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, 2007, Weinheim. doi:10.1002/14356007.a11_349
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