Oleyl alcohol

Oleyl alcohol /ˈoʊliˌɪl, ˈoʊliəl/,[1] octadecenol /ˌɒktəˈdɛsɪˌnɒl/, or cis-9-octadecen-1-ol, is an unsaturated fatty alcohol with the molecular formula C18H36O or the condensed structural formula CH3(CH2)7-CH=CH-(CH2)8OH. It is a colorless oil, mainly used in cosmetics.[2]

Oleyl alcohol
Names
IUPAC name
(Z)-Octadec-9-en-1-ol
Other names
Octadecenol
cis-9-Octadecen-1-ol
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.005.089
KEGG
UNII
Properties
C18H36O
Molar mass 268.478 g/mol
Density 0.845-0.855 g/cm3
Melting point 13 to 19 °C (55 to 66 °F; 286 to 292 K)
Boiling point 330 to 360 °C (626 to 680 °F; 603 to 633 K)
Insoluble
Hazards
NFPA 704 (fire diamond)
Flammability code 0: Will not burn. E.g. waterHealth code 1: Exposure would cause irritation but only minor residual injury. E.g. turpentineReactivity code 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
0
1
0
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

It can be produced by the hydrogenation of oleic acid esters by Bouveault–Blanc reduction, which avoids reduction of the C=C group (as would occur with usual catalytic hydrogenation). The required oleate esters are obtained from beef fat, fish oil, and, in particular, olive oil (from which it gains its name). The original procedure was reported by Louis Bouveault in 1904[3] and subsequently refined.[4][5]

It has uses as a nonionic surfactant, emulsifier, emollient and thickener in skin creams, lotions and many other cosmetic products including shampoos and hair conditioners. It has also been investigated as a carrier for delivering medications through the skin or mucus membranes; particularly the lungs.[6]

See also

References
  1. "Oleyl" in the McGraw–Hill Dictionary of Scientific & Technical Terms (2003)
  2. Noweck, Klaus; Grafahrend, Wolfgang (2006). "Fatty Alcohols". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a10_277.pub2.
  3. Bouveault, L.; Blanc, G. (1904). "Hydrogénation des éthers des acides possédant en outre les fonctions éther-oxyde ou acétal" [Hydrogenation of the ether of the acids furthermore possessing the ether-oxide or acetal functions]. Bull. Soc. Chim. Fr. (in French). 31 (3): 1210–1213.
  4. Reid, E. E.; Cockerille, F. O.; Meyer, J. D.; Cox, W. M.; Ruhoff, J. R. (1935). "Oleyl Alcohol". Organic Syntheses. 15: 51. doi:10.15227/orgsyn.015.0051.; Collective Volume, 2, p. 468
  5. Adkins, Homer; Gillespie, R. H. (1935). "Oleyl alcohol". Org. Synth. 29: 51. doi:10.15227/orgsyn.015.0051.
  6. Hussain, Alamdar; Arnold, John J.; Khan, Mansoor A.; Ahsan, Fakhrul (2004). "Absorption enhancers in pulmonary protein delivery". J. Control. Release. 94 (1): 15–24. doi:10.1016/j.jconrel.2003.10.001. PMID 14684268.
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