Peroxin

Peroxin
Identifiers
Symbol PEX-2,10,12
Membranome 190
Peroxin 11
Identifiers
Symbol PEX-11
Pfam PF05648
InterPro IPR008733
Membranome 191
Peroxin 13
Identifiers
Symbol PEX-13
Pfam PF04088
InterPro IPR007223
Membranome 192
Peroxin 14
Identifiers
Symbol PEX-14
InterPro IPR025655
Membranome 468

Peroxins (or peroxisomal/peroxisome biogenesis factors) represent several protein families found in peroxisomes. Deficiencies are associated with several peroxisomal disorders. Peroxins serve several functions including the recognition of cytoplasmic proteins that contain peroxisomal targeting signals (PTS) that tag them for transport by peroxisomal proteins to the peroxisome. Peroxins are structurally diverse and have been classified to different protein families. Some of them were predicted to be single-pass transmembrane proteins, for example Peroxisomal biogenesis factor 11.

Genes

"PEX2" is now known as "peroxisomal membrane protein 3", or PXMP3.

References

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