MTMR6

MTMR6
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMTMR6, myotubularin related protein 6
External IDsMGI: 2145637 HomoloGene: 55842 GeneCards: MTMR6
Gene location (Human)
Chr.Chromosome 13 (human)[1]
Band13q12.13Start25,246,201 bp[1]
End25,288,009 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

9107

219135

Ensembl

ENSG00000139505

ENSMUSG00000021987

UniProt

Q9Y217

Q8VE11

RefSeq (mRNA)

NM_004685

NM_144843

RefSeq (protein)

NP_004676

NP_659092

Location (UCSC)Chr 13: 25.25 – 25.29 MbChr 14: 60.27 – 60.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Myotubularin-related protein 6 is a protein that in humans is encoded by the MTMR6 gene.[5][6]

Interactions

MTMR6 has been shown to interact with MTMR9.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000139505 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021987 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Laporte J, Blondeau F, Buj-Bello A, Tentler D, Kretz C, Dahl N, Mandel JL (Dec 1998). "Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human". Hum. Mol. Genet. 7 (11): 1703–12. doi:10.1093/hmg/7.11.1703. PMID 9736772.
  6. ↑ "Entrez Gene: MTMR6 myotubularin related protein 6".
  7. ↑ Mochizuki Y, Majerus PW (Aug 2003). "Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9". Proc. Natl. Acad. Sci. U.S.A. 100 (17): 9768–73. doi:10.1073/pnas.1333958100. PMC 187840. PMID 12890864.

Further reading

  • Hartley JL, Temple GF, Brasch MA (2000). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Schaletzky J, Dove SK, Short B, Lorenzo O, Clague MJ, Barr FA (2003). "Phosphatidylinositol-5-phosphate activation and conserved substrate specificity of the myotubularin phosphatidylinositol 3-phosphatases". Curr. Biol. 13 (6): 504–9. doi:10.1016/S0960-9822(03)00132-5. PMID 12646134.
  • Nandurkar HH, Layton M, Laporte J, Selan C, Corcoran L, Caldwell KK, Mochizuki Y, Majerus PW, Mitchell CA (2003). "Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP". Proc. Natl. Acad. Sci. U.S.A. 100 (15): 8660–5. doi:10.1073/pnas.1033097100. PMC 166368. PMID 12847286.
  • Mochizuki Y, Majerus PW (2003). "Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9". Proc. Natl. Acad. Sci. U.S.A. 100 (17): 9768–73. doi:10.1073/pnas.1333958100. PMC 187840. PMID 12890864.
  • Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • Srivastava S, Ko K, Choudhury P, Li Z, Johnson AK, Nadkarni V, Unutmaz D, Coetzee WA, Skolnik EY (2006). "Phosphatidylinositol-3 phosphatase myotubularin-related protein 6 negatively regulates CD4 T cells". Mol. Cell. Biol. 26 (15): 5595–602. doi:10.1128/MCB.00352-06. PMC 1592754. PMID 16847315.
  • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.


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