AGN-2979
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Formula | C19H28N2O3 |
Molar mass | 332.44 g/mol |
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AGN-2979 is a glutarimide tryptophan hydroxylase activation inhibitor.[1][2] It shows antidepressant properties in rodent models of depression.[2]
References
- ↑ Hasegawa, S; Kanemaru, K; Gittos, M; Diksic, M (15 October 2005). "The Tryptophan Hydroxylase Activation Inhibitor, AGN-2979, Decreases Regional 5-HT Synthesis in the Rat Brain Measured with α-[14C]methyl-L-tryptophan: an Autoradiographic Study". Brain Research Bulletin. 67 (3): 248–55. doi:10.1016/j.brainresbull.2005.07.009. PMID 16144662.
- 1 2 Gittos, MW; Papp, M (October 2001). "Antidepressant-like Action of AGN 2979, a Tryptophan Hydroxylase Activation Inhibitor, in a Chronic Mild Stress Model of Depression in Rats". European Neuropsychopharmacology. 11 (5): 351–7. doi:10.1016/S0924-977X(01)00103-1. PMID 11597821.
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