Nitecapone

Nitecapone (INN; OR-462) is a drug which acts as a selective inhibitor of the enzyme catechol O-methyl transferase (COMT).[1][2] It was patented as an antiparkinson medication but was never marketed.[1]

Nitecapone
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC12H11NO6
Molar mass265.221 g·mol−1
3D model (JSmol)

See also

References

  1. F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 1635. ISBN 978-0-412-46630-4. Retrieved 20 May 2012.
  2. Nissinen E, Lindén IB, Schultz E, Kaakkola S, Männistö PT, Pohto P (August 1988). "Inhibition of catechol-O-methyltransferase activity by two novel disubstituted catechols in the rat". European Journal of Pharmacology. 153 (2–3): 263–9. doi:10.1016/0014-2999(88)90614-0. PMID 3181288.


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