Normetanephrine

Normetanephrine is a metabolite of norepinephrine created by action of catechol-O-methyl transferase on norepinephrine. It is excreted in the urine and found in certain tissues. It is a marker for catecholamine-secreting tumors such as pheochromocytoma.

Norepinephrine degradation. Normetanephrine is shown at top left. Enzymes are shown in boxes.[1]
Normetanephrine
Names
IUPAC name
4-(2-amino-1-hydroxy-ethyl)- 2-methoxy-phenol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
MeSH Normetanephrine
UNII
Properties
C9H13NO3
Molar mass 183.204 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

References

  1. Figure 11-4 in: Flower, R.; Rang, H. P.; Dale, M. M.; Ritter, J. M. (2007). Rang & Dale's Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-06911-5.


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