Dexetimide

Dexetimide (brand name Tremblex) is a piperidine anticholinergic. It is a muscarinic antagonist that is used to treat drug induced parkinsonism. Dexetimide was discovered at Janssen Pharmaceutica in 1968.[1][2]

Dexetimide
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Chemical and physical data
FormulaC23H26N2O2
Molar mass362.473 g·mol−1
3D model (JSmol)
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References

  1. Dom R, Van Lommel R, Baro F (1971). "A quantitative study of neuroleptic-induced extrapyramidal symptoms and their response to dexetimide, a potent and long-acting antiparkinsonian agent". Acta Psychiatrica Scandinavica. 47 (4): 399–410. doi:10.1111/j.1600-0447.1971.tb03697.x. PMID 4947805.
  2. Huygens H, Vereecken JL, Tanghe A (1973). "Dexetimide (R 16470) in the control of neuroleptic-induced extrapyramidal side-effects. Its prophylactic value and duration of action". Psychiatria, Neurologia, Neurochirurgia. 76 (4): 251–9. PMID 4581374.
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