GFRA4

GDNF family receptor alpha-4 (GFRα4), also known as the persephin receptor, is a protein that in humans is encoded by the GFRA4 gene.[5]

GFRA4
Identifiers
Aliases	GFRA4, GDNF family receptor alpha 4
External IDs	MGI: 1341873 HomoloGene: 10565 GeneCards: GFRA4
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20p13 Start 3,659,292 bp[1] End 3,663,399 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2 F1|2 63.26 cM Start 131,039,632 bp[2] End 131,043,088 bp[2]
Gene ontology Molecular function • glial cell-derived neurotrophic factor receptor activity • Ras guanyl-nucleotide exchange factor activity • signaling receptor activity Cellular component • extracellular region • membrane • anchored component of membrane • cell membrane • intracellular • extracellular • external side of plasma membrane • receptor complex Biological process • negative regulation of ossification • glial cell-derived neurotrophic factor receptor signaling pathway • MAPK cascade • axon guidance • nervous system development Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	64096	14588
Ensembl	ENSG00000125861	ENSMUSG00000027316
UniProt	Q9GZZ7	Q9JJT2
RefSeq (mRNA)	NM_022139 NM_145762 NM_145763	NM_001136063 NM_001271001 NM_001271002 NM_020014
RefSeq (protein)	NP_071422 NP_665705	NP_001129535 NP_001257930 NP_001257931 NP_064398
Location (UCSC)	Chr 20: 3.66 – 3.66 Mb	Chr 2: 131.04 – 131.04 Mb
PubMed search	[3]	[4]
Wikidata
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