Diosmetin
Diosmetin, also known as 5,7,3'-trihydroxy-4'-methoxyflavone, is an O-methylated flavone, a chemical compound that can be found in the Caucasian vetch.[1]
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| Names | |
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| IUPAC name
5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one | |
| Other names
Luteolin 4'-methyl ether 3′,5,7-trihydroxy-4′-methoxyflavone | |
| Identifiers | |
3D model (JSmol) |
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| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.007.539 |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C16H12O6 | |
| Molar mass | 300.26 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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| Infobox references | |
It has been found to act as a weak TrkB receptor agonist.[2]
Glycosides
Diosmetin is the diosmin aglycone.
References
- Diosmetin glycosides from caucasian vetch: Isolation and study of biological activity
O. A. Andreeva, M. N. Ivashev, I. I. Ozimina and G. V. Maslikova, 1994 - Jang SW, Liu X, Yepes M, Shepherd KR, Miller GW, Liu Y, Wilson WD, Xiao G, Blanchi B, Sun YE, Ye K (2010). "A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone". Proc. Natl. Acad. Sci. U.S.A. 107 (6): 2687–92. doi:10.1073/pnas.0913572107. PMC 2823863. PMID 20133810.
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