GFRα
The GDNF family receptor-α (GFRα) proteins are a group of co-receptors which form complexes with GDNF-family ligands (GFLs) to activate RET, the receptor of the GFLs.[1] The GFRα co-receptors include the following:
- GFRα1 – preference for GDNF
- GFRα2 – preference for neurturin
- GFRα3 – preference for artemin
- GFRα4 – preference for persephin
- GFRAL - receptor for GDF15
| Glial cell line-derived neurotrophic factor receptor | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | GFRα | ||||||||
| Pfam | PF02351 | ||||||||
| InterPro | IPR003438 | ||||||||
| Membranome | 44 | ||||||||
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References
| Neurotrophins | |
|---|---|
| GDNF family | |
| Ephrins | |
| CNTF family | |
| Other | |
| Angiopoietin |
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|---|---|---|---|---|---|---|---|---|---|---|---|
| CNTF | |||||||||||
| EGF (ErbB) |
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| FGF |
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| HGF (c-Met) |
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| IGF |
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| LNGF (p75NTR) |
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| PDGF |
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| RET (GFL) |
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| SCF (c-Kit) | |||||||||||
| TGFβ |
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| Trk |
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| VEGF |
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| Others |
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