Nesvacumab
Nesvacumab is an experimental monoclonal antibody originally designed for the treatment of cancer. It targets the protein angiopoietin 2.[1] As of May 2017, it is in Phase II clinical trials for the treatment of diabetic macular edema.[2][3]
| Monoclonal antibody | |
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| Type | Whole antibody |
| Source | Human |
| Target | Angiopoietin 2 |
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| Formula | C6440H9966N1722O2008S38 |
| Molar mass | 144860.89 g·mol−1 |
This drug is being developed by Regeneron Pharmaceuticals.
References
- Statement On A Nonproprietary Name Adopted By The USAN Council - Nesvacumab, American Medical Association.
- Clinical trial number NCT02713204 for "Anti-angiOpoeitin 2 Plus Anti-vascular eNdothelial Growth Factor as a therapY for Neovascular Age Related Macular Degeneration: Evaluation of a fiXed Combination Intravitreal Injection (ONYX)" at ClinicalTrials.gov
- Clinical trial number NCT02712008 for "Anti-vasculaR Endothelial Growth Factor plUs Anti-angiopoietin 2 in Fixed comBination therapY: Evaluation for the Treatment of Diabetic Macular Edema (RUBY)" at ClinicalTrials.gov
Monoclonals for bone, musculoskeletal, circulatory, and neurologic systems | |||||||||
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| Bone ("-os-", "-s(o)-") |
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| Musculoskeletal ("-mul-") |
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| Circulatory ("-c(i[r])-") |
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| Neurologic ("-ne(u)(r)-") |
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| Angiogenesis inhibitor ("-anibi-") |
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| Growth factor ("-gr(o)-") |
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| Angiopoietin |
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