GFRAL

GFRAL
Identifiers
Aliases	GFRAL, C6orf144, GRAL, UNQ9356, bA360D14.1, GDNF family receptor alpha like
External IDs	OMIM: 617837 MGI: 3607786 HomoloGene: 45748 GeneCards: GFRAL
Gene location (Human)
Chr.	Chromosome 6 (human)[1]
End	55,402,493 bp[1]
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)[2]
End	76,213,657 bp[2]
Gene ontology
Molecular function	• signaling receptor activity; • GO:0001948 protein binding; • glial cell-derived neurotrophic factor receptor activity; • receptor tyrosine kinase binding;
Cellular component	• integral component of membrane; • cell membrane; • intracellular; • membrane; • external side of plasma membrane; • receptor complex;
Biological process	• negative regulation of neuron apoptotic process; • stress-activated protein kinase signaling cascade; • negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; • activation of MAPK activity; • reduction of food intake in response to dietary excess; • glial cell-derived neurotrophic factor receptor signaling pathway; • positive regulation of MAPK cascade; • positive regulation of protein kinase B signaling; • nervous system development;
	Sources:Amigo / QuickGO
Orthologs
	389400
	404194
	ENSG00000187871
	ENSMUSG00000059383
	Q6UXV0
	Q6SJE0
	NM_207410
	NM_205844
	NP_997293
	NP_995316
	Wikidata
View/Edit Human	View/Edit Mouse

GDNF family receptor alpha like is a protein that in humans is encoded by the GFRAL gene. [5]

References

GRCh38: Ensembl release 89: ENSG00000187871 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000059383 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: GDNF family receptor alpha like". Retrieved 2017-09-04.

Overview of all the structural information available in the PDB for UniProt: Q6UXV0 (GDNF family receptor alpha-like) at the PDBe-KB.

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