GAT100
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|---|---|
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| CAS Number | |
| ChemSpider | |
| Chemical and physical data | |
| Formula | C25H28N4OS |
| Molar mass | 432.59 g·mol−1 |
| 3D model (JSmol) | |
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GAT100 is a negative allosteric modulator of the cannabinoid CB1 receptor.[1][2]
See also
References
- ↑ Pushkar M. Kulkarni; Abhijit R. Kulkarni; Anisha Korde; Ritesh B. Tichkule; Robert B. Laprairie; Eileen M. Denovan-Wright; Han Zhou∥; David R. Janero; Nikolai Zvonok; Alexandros Makriyannis; Maria G. Cascio; Roger G. Pertwee; Ganesh A. Thakur (January 2016). "Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s)". Journal of Medicinal Chemistry. 59 (1): 44–60. doi:10.1021/acs.jmedchem.5b01303. PMC 4716578. PMID 26529344.
- ↑ Robert B. Laprairie; Abhijit R. Kulkarni; Pushkar M. Kulkarni; Dow P. Hurst; Diane Lynch; Patricia H. Reggio; David R. Janero; Roger G. Pertwee; Lesley A. Stevenson; Melanie E. M. Kelly; Eileen M. Denovan-Wright; Ganesh A. Thakur (April 2016). "Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe". ACS Chemical Neuroscience. 7: 776–98. doi:10.1021/acschemneuro.6b00041. PMC 5358098. PMID 27046127.
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