EPHA10

EPHA10
Identifiers
Aliases	EPHA10, EPH receptor A10
External IDs	MGI: 3586824 HomoloGene: 67804 GeneCards: EPHA10
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	37,765,133 bp[1]
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)[2]
End	124,917,800 bp[2]
Gene ontology
Molecular function	• transferase activity; • nucleotide binding; • protein kinase activity; • transmembrane-ephrin receptor activity; • kinase activity; • protein binding; • transmembrane receptor protein tyrosine kinase activity; • protein tyrosine kinase activity; • ATP binding; • ephrin receptor activity; • receptor tyrosine kinase; • transmembrane signaling receptor activity;
Cellular component	• integral component of membrane; • membrane; • plasma membrane; • integral component of plasma membrane; • extracellular region; • cytoplasm; • neuron projection; • receptor complex;
Biological process	• phosphorylation; • transmembrane receptor protein tyrosine kinase signaling pathway; • protein phosphorylation; • peptidyl-tyrosine phosphorylation; • ephrin receptor signaling pathway; • biological process; • negative regulation of signal transduction; • cell differentiation; • negative regulation of apoptotic process; • positive regulation of ERK1 and ERK2 cascade;
	Sources:Amigo / QuickGO
Orthologs
	284656
	230735
	ENSG00000183317
	ENSMUSG00000028876
	Q5JZY3
	Q8BYG9
	NM_001004338; NM_001099439; NM_173641
	NM_001256432; NM_177671
	NP_001092909; NP_775912
	NP_001243361; NP_808339
	Wikidata
View/Edit Human	View/Edit Mouse

EPH receptor A10 is a protein in humans that is encoded by the EPHA10 gene.^[5]

Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells.^[5] See MIM 179610 for additional background on Eph receptors and ephrins.^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000183317 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028876 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
1 2 Aasheim HC, Patzke S, Hjorthaug HS, Finne EF (May 2005). "Characterization of a novel Eph receptor tyrosine kinase, EphA10, expressed in testis". Biochimica et Biophysica Acta. 1723 (1–3): 1–7. doi:10.1016/j.bbagen.2005.01.011. PMID 15777695.
↑ "MIM 179610". Online Mendelian Inheritance in Man. January 5, 2010. Retrieved August 6, 2013.

EPHA10

References

Further reading