Coatomer
The coatomer is a protein complex[1] that coats membrane-bound transport vesicles. Two types of coatomers are known:
- COPI (retrograde transport from trans-Golgi network to cis-Golgi network and endoplasmic reticulum)
- COPII (anterograde transport from ER to the cis-Golgi)
Coatomers are functionally analogous and evolutionarily homologous to clathrin adaptor proteins, also known as adaptins,[2] which regulate endocytosis from the plasma membrane and transport from the trans-Golgi network to lysosomes.
References
- ↑ Coatomer+Protein at the US National Library of Medicine Medical Subject Headings (MeSH)
- ↑ Boehm, Markus; Bonifacino, Juan S. (October 2001). "Adaptins". Molecular Biology of the Cell. 12 (10): 2907–2920. doi:10.1091/mbc.12.10.2907. ISSN 1059-1524. PMC 60144. PMID 11598180.
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