Zardaverine

Zardaverine
Names
IUPAC name
3-[4-(Difluoromethoxy)-3-methoxyphenyl]-1H-pyridazin-6-one
Identifiers
3D model (JSmol)
ChemSpider
Properties
C12H10F2N2O3
Molar mass 268.22 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Zardaverine is a dual-selective PDE3/4 phosphodiesterase inhibitor.[1]

References

  1. Kümmerle, AE; Schmitt, M; Cardozo, SV; Lugnier, C; Villa, P; Lopes, AB; Romeiro, NC; Justiniano, H; Martins, MA; Fraga, CA; Bourguignon, JJ; Barreiro, EJ (2012). "Design, Synthesis, and Pharmacological Evaluation of N-Acylhydrazones and Novel Conformationally Constrained Compounds as Selective and Potent Orally Active Phosphodiesterase-4 Inhibitors". Journal of Medicinal Chemistry. 55 (17): 7525–45. doi:10.1021/jm300514y. PMID 22891752.
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