S-Adenosyl-L-homocysteine
Names | |
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IUPAC name
S-(5'-Deoxyadenos-5'-yl)-L-homocysteine | |
Other names
AdoHcy, 2-S-adenosyl-L-homocysteine, 5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine S-adenosylhomocysteine, SAH | |
Identifiers | |
3D model (JSmol) |
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.012.328 |
KEGG | |
MeSH | S-Adenosylhomocysteine |
PubChem CID |
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Properties | |
C14H20N6O5S | |
Molar mass | 384.412 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
S-Adenosyl-L-homocysteine (SAH) is an amino acid derivative used in several metabolic pathways in most organisms. It is an intermediate in the synthesis of cysteine and adenosine.[1]
SAH is formed by the demethylation of S-adenosyl-L-methionine and is converted to homocysteine and adenosine by adenosylhomocysteinase.
References
- ↑ James, S. Jill; Melnyk, Stepan; Pogribna, Marta; Pogribny, Igor P; Caudill, Marie A (2002). "Elevation in S-Adenosylhomocysteine and DNA Hypomethylation: Potential Epigenetic Mechanism for Homocysteine-Related Pathology". The Journal of Nutrition. 132 (8): 2361S–2366S. doi:10.1093/jn/132.8.2361S.
External links
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