S-Adenosyl-L-homocysteine

S-Adenosyl-L-homocysteine
Names
IUPAC name
S-(5'-Deoxyadenos-5'-yl)-L-homocysteine
Other names
AdoHcy, 2-S-adenosyl-L-homocysteine,
5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine S-adenosylhomocysteine, SAH
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.012.328
KEGG
MeSH S-Adenosylhomocysteine
Properties
C14H20N6O5S
Molar mass 384.412
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

S-Adenosyl-L-homocysteine (SAH) is an amino acid derivative used in several metabolic pathways in most organisms. It is an intermediate in the synthesis of cysteine and adenosine.[1]

SAH is formed by the demethylation of S-adenosyl-L-methionine and is converted to homocysteine and adenosine by adenosylhomocysteinase.

References

  1. James, S. Jill; Melnyk, Stepan; Pogribna, Marta; Pogribny, Igor P; Caudill, Marie A (2002). "Elevation in S-Adenosylhomocysteine and DNA Hypomethylation: Potential Epigenetic Mechanism for Homocysteine-Related Pathology". The Journal of Nutrition. 132 (8): 2361S–2366S. doi:10.1093/jn/132.8.2361S.
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