Glutamate-1-semialdehyde

Glutamate-1-semialdehyde
Names
	IUPAC name (4S)-4-Amino-5-oxo-pentanoic acid
Identifiers
CAS Number	68462-55-5 ;
3D model (JSmol)	Interactive image;
ChemSpider	114525 ;
MeSH	glutamate-1-semialdehyde
PubChem CID	129297;
	InChI InChI=1S/C5H9NO3/c6-4(3-7)1-2-5(8)9/h3-4H,1-2,6H2,(H,8,9)/t4-/m0/s1 Key: MPUUQNGXJSEWTF-BYPYZUCNSA-N ; InChI=1/C5H9NO3/c6-4(3-7)1-2-5(8)9/h3-4H,1-2,6H2,(H,8,9)/t4-/m0/s1 Key: MPUUQNGXJSEWTF-BYPYZUCNBY;
	SMILES C(CC(=O)O)[C@@H](C=O)N;
Properties
Chemical formula	C5H9NO3
Molar mass	131.13 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

Glutamate-1-semialdehyde is a molecule formed from by the reduction of tRNA bound glutamate, catalyzed by glutamyl-tRNA reductase. It is isomerized by glutamate-1-semialdehyde 2,1-aminomutase to give aminolevulinic acid in the biosynthesis of porphyrins, including heme and chlorophyll.^[1]^[2]

References

↑ Beale SI (August 1990). "Biosynthesis of the Tetrapyrrole Pigment Precursor, delta-Aminolevulinic Acid, from Glutamate". Plant Physiol. 93 (4): 1273–9. doi:10.1104/pp.93.4.1273. PMC 1062668. PMID 16667613.
↑ Willows, R.D. (2004). "Chlorophylls". In Goodman, Robert M. Encyclopaedia of Plant and Crop Science. Marcel Dekker. pp. 258–262. ISBN 0-8247-4268-0.

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