RNPEP

RNPEP
Identifiers
AliasesRNPEP, AP-B, arginyl aminopeptidase, APB
External IDsMGI: 2384902 HomoloGene: 10628 GeneCards: RNPEP
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1q32.1Start201,982,372 bp[1]
End202,006,147 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

6051

215615

Ensembl

ENSG00000176393

ENSMUSG00000041926

UniProt

Q9H4A4

Q8VCT3

RefSeq (mRNA)

NM_020216
NM_001319182
NM_001319183
NM_001319184

NM_001159624
NM_145417

RefSeq (protein)

NP_001306111
NP_001306112
NP_001306113
NP_064601

NP_001153096
NP_663392

Location (UCSC)Chr 1: 201.98 – 202.01 MbChr 1: 135.26 – 135.28 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Aminopeptidase B is an enzyme that in humans is encoded by the RNPEP gene.[5][6][7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000176393 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041926 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Aurich-Costa J, Cadel S, Gouzy C, Foulon T, Cherif D, Cohen P (Apr 1998). "Assignment of the aminopeptidase B gene (RNPEP) to human chromosome 1 band q32 by in situ hybridization". Cytogenet Cell Genet. 79 (1–2): 143–4. doi:10.1159/000134703. PMID 9533033.
  6. ↑ Foulon T, Cadel S, Cohen P (Oct 1999). "Aminopeptidase B (EC 3.4.11.6)". Int J Biochem Cell Biol. 31 (7): 747–50. doi:10.1016/S1357-2725(99)00021-7. PMID 10467730.
  7. ↑ "Entrez Gene: RNPEP arginyl aminopeptidase (aminopeptidase B)".

Further reading

  • Belhacene N, Mari B, Rossi B, Auberger P (1993). "Characterization and purification of T lymphocyte aminopeptidase B: a putative marker of T cell activation". Eur. J. Immunol. 23 (8): 1948–55. doi:10.1002/eji.1830230833. PMID 8344358.
  • Gress TM, Müller-Pillasch F, Geng M, et al. (1996). "A pancreatic cancer-specific expression profile". Oncogene. 13 (8): 1819–30. PMID 8895530.
  • Balogh A, Cadel S, Foulon T, et al. (1998). "Aminopeptidase B: a processing enzyme secreted and associated with the plasma membrane of rat pheochromocytoma (PC12) cells". J. Cell Sci. 111 (2): 161–9. PMID 9405297.
  • Piesse C, Tymms M, Garrafa E, et al. (2002). "Human aminopeptidase B (rnpep) on chromosome 1q32.2: complementary DNA, genomic structure and expression". Gene. 292 (1–2): 129–40. doi:10.1016/S0378-1119(02)00650-9. PMID 12119107.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Fukasawa KM, Hirose J, Hata T, Ono Y (2006). "Aspartic acid 405 contributes to the substrate specificity of aminopeptidase B". Biochemistry. 45 (38): 11425–31. doi:10.1021/bi0604577. PMID 16981702.
  • The MEROPS online database for peptidases and their inhibitors: M01.014


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.