Flavonoid 4'-O-methyltransferase

Flavonoid 4'-O-methyltransferase
Identifiers
EC number 2.1.1.231
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Flavonoid 4'-O-methyltransferase (EC 2.1.1.231, SOMT-2, 4'-hydroxyisoflavone methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + 4'-hydroxyflavanone S-adenosyl-L-homocysteine + 4'-methoxyflavanone

The enzyme catalyses the 4'-methylation of naringenin.

References

  1. Kim, D.H.; Kim, B.G.; Lee, Y.; Ryu, J.Y.; Lim, Y.; Hur, H.G.; Ahn, J.H. (2005). "Regiospecific methylation of naringenin to ponciretin by soybean O-methyltransferase expressed in Escherichia coli". J. Biotechnol. 119 (2): 155–162. doi:10.1016/j.jbiotec.2005.04.004. PMID 15961179.
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