EVT-103

EVT-103
Clinical data
Synonyms ENS-103
Routes of
administration
By mouth
Drug class NMDA receptor antagonist

EVT-103, also known as ENS-103, is an experimental medication which originated from Roche and is under development by Evotec AG for the treatment of major depressive disorder.[1] It acts as an NMDA receptor subunit 2B (NR2B) antagonist.[1] As of November 2017, no recent reports of development for major depressive disorder have been identified.[1] The drug was developed as a follow-up compound to EVT-101.[2] The chemical structure of EVT-103 has not been released.[2]

See also

References

  1. 1 2 3 http://adisinsight.springer.com/drugs/800030864
  2. 1 2 Ruppa, Kamalesh B.; King, Dalton; Olson, Richard E. (2012). "NMDA Antagonists of GluN2B Subtype and Modulators of GluN2A, GluN2C, and GluN2D Subtypes—Recent Results and Developments". 47: 89–103. doi:10.1016/B978-0-12-396492-2.00007-2. ISSN 0065-7743.



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