CNQX

CNQX

Names
IUPAC name 7-nitro-2,3-dioxo-1,4- dihydroquinoxaline-6-carbonitrile
Identifiers
CAS Number	115066-14-3 Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL222418 Y
ChemSpider	2951930 Y
IUPHAR/BPS	5475
KEGG	C13668 Y
PubChem CID	3721046
UNII	6OTE87SCCW Y
InChI InChI=1S/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15) Y Key: RPXVIAFEQBNEAX-UHFFFAOYSA-N Y InChI=1/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15) Key: RPXVIAFEQBNEAX-UHFFFAOYAV
SMILES [O-][N+](=O)c1c(C#N)cc2c(c1)NC(=O)C(=O)N2
Properties
Chemical formula	C9H4N4O4
Molar mass	232.15 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references

CNQX or cyanquixaline (6-cyano-7-nitroquinoxaline-2,3-dione) is a competitive AMPA/kainate receptor antagonist. Its chemical formula is C₉H₄N₄O₄. CNQX is often used in the retina to block the responses of OFF-bipolar cells for electrophysiology recordings.^[1]

See also

• Quinoxalinedione

References

External links

• Imamachi et al. : The Non-NMDA Glutamate Receptor Antagonist CNQX Augments Lidocaine Antinociception Through a Spinal Action in Rats
• Chemical structure