Dominic Kwiatkowski

Dominic Kwiatkowski
FRS FMedSci FRCP
Dominic Kwiatkowski in 2013
Born Dominic P. Kwiatkowski
Scientific career
Fields Genomics
Malaria[1][2]
Institutions Wellcome Sanger Institute
University of Cambridge
University of Oxford
Guy's Hospital
Leyland Motors[3]
Influences Charles A. Dinarello[4]
Brian Greenwood[4]
Website sanger.ac.uk/people/directory/kwiatkowski-dominic

Dominic Kwiatkowski FRS FMedSci FRCP[5][6] is head of the parasites and microbes programme at the Wellcome Sanger Institute[3] in Cambridge and a Professor of Genomics at the University of Oxford.[5] Kwiatkowski applies genomics and computational analysis to problems in infectious disease, with the aim of finding ways to reduce the burden of disease in the developing world.[5][4][7]

After training as a paediatrician at Guy's Hospital in London, Kwiatkowski spent several years in West Africa, where malaria causes high levels of infant mortality, and this has been a major focus of his research over the past thirty years.[5] He has made significant contributions to the understanding of malaria pathogenesis and genetic mechanisms of resistance to the disease.[5] He has also pioneered genome-wide association studies (GWAS) in Africa and has led large international collaborations to characterise the genomic diversity of parasite and mosquito populations around the world.[5] This work is yielding deep insights into the evolutionary biology of drug resistance and pesticide resistance with practical implications for disease control.[5]

In 2005 Kwiatkowski founded a data-sharing network, MalariaGEN, which has fostered productive research collaborations in more than forty malaria endemic countries, and has become a model for equitable sharing of genetic data and research capacity building in resource-poor settings.[5][1]

References

  1. 1 2 Hill, Adrian V. S.; Allsopp, Catherine E. M.; Kwiatkowski, Dominic; Anstey, Nicholas M.; Twumasi, Patrick; Rowe, Pamela A.; Bennett, Stephen; Brewster, David; McMichael, Andrew J.; Greenwood, Brian M. (1991). "Common West African HLA antigens are associated with protection from severe malaria". Nature. 352 (6336): 595–600. doi:10.1038/352595a0. ISSN 0028-0836. PMID 1865923.
  2. ↑ Kwiatkowski, Dominic P. (2005). "How malaria has affected the human genome and what human genetics can teach us about malaria". American Journal of Human Genetics. 77 (2): 171–92. doi:10.1086/432519. PMC 1224522. PMID 16001361.
  3. 1 2 "Kwiatkowski, Dominic". sanger.ac.uk.
  4. 1 2 3 "Professor Dominic Kwiatkowski - Nuffield Department of Medicine". www.ndm.ox.ac.uk.
  5. 1 2 3 4 5 6 7 8 Anon (2018). "Professor Dominic Kwiatkowski FMedSci FRS". royalsociety.org. London: Royal Society. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
    “All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --Royal Society Terms, conditions and policies at the Wayback Machine (archived 2016-11-11)
  6. ↑ "Professor Dominic Kwiatkowski - The Academy of Medical Sciences". acmedsci.ac.uk.
  7. ↑ Dominic Kwiatkowski publications from Europe PubMed Central

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