Dimethylglycine N-methyltransferase

Dimethylglycine N-methyltransferase
Identifiers
EC number 2.1.1.161
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Dimethylglycine N-methyltransferase (EC 2.1.1.161, BsmB, DMT) is an enzyme with systematic name S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase (betaine-forming).[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + N,N-dimethylglycine S-adenosyl-L-homocysteine + betaine

This enzyme is purified from the marine cyanobacterium Synechococcus sp. WH8102.

References

  1. Lu, W.D.; Chi, Z.M.; Su, C.D. (2006). "Identification of glycine betaine as compatible solute in Synechococcus sp. WH8102 and characterization of its N-methyltransferase genes involved in betaine synthesis". Arch. Microbiol. 186 (6): 495–506. doi:10.1007/s00203-006-0167-8. PMID 17019606.


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