Deoxyribonuclease (pyrimidine dimer)
| Deoxyribonuclease (pyrimidine dimer) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.1.25.1 | ||||||||
| CAS number | 66143-22-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Deoxyribonuclease (pyrimidine dimer) (EC 3.1.25.1, endodeoxyribonuclease (pyrimidine dimer), bacteriophage T4 endodeoxyribonuclease V, T4 endonuclease V) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
- Endonucleolytic cleavage near pyrimidine dimers to products with 5'-phosphate
This enzyme acts on a damaged strand, 5' from the damaged site.
References
- ↑ Braun, A.G.; Radman, M.; Grossman, L. (1976). "Enzymic repair of DNA: sites of hydrolysis by the Escherichia coli endonuclease specific for pyrimidine dimers (corendonuclease II)". Biochemistry. 15 (18): 4116–4120. doi:10.1021/bi00663a031. PMID 786366.
- ↑ Riazuddin, S.; Grossman, L. (1977). "Micrococcus luteus correndonucleases. II. Mechanism of action of two endonucleases specific for DNA containing pyrimidine dimers". J. Biol. Chem. 252 (18): 6287–6293. PMID 330526.
External links
- Deoxyribonuclease+(pyrimidine+dimer) at the US National Library of Medicine Medical Subject Headings (MeSH)
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