Calcium/cholecalciferol

Calcium/cholecalciferol
Combination of
Calcium Mineral nutrient
Cholecalciferol Vitamin
Clinical data
AHFS/Drugs.com Multum Consumer Information
Pregnancy
category
  • US: C (Risk not ruled out)
    Routes of
    administration    		 Oral
    ATC code
    Legal status
    Legal status

    Calcium/cholecalciferol is a combination of a calcium salt (usually calcium carbonate) and vitamin D3 (cholecalciferol), available under many brand names and in many forms such as chewable tablets, coated tablets, and effervescent tablets. It is used to prevent and treat lack of calcium and vitamin D in the elderly, as well as adjunctive therapy for osteoporosis.[1][2]

    Adverse effects and overdose

    Possible side effects include gastrointestinal problems, for example nausea and constipation. If very high doses are taken, signs of hypercalcaemia (too high blood calcium levels) have been described, such as stomach pain, vomiting, thirst, and tiredness. Extreme or long-term or overdose can theoretically result in hypervitaminosis D, kidney stones, renal insufficiency and calcinosis.[1][2]

    Interactions

    Calcium forms complexes with a number of pharmaceutical drugs, reducing their bioavailability; among them are tetracyclines, quinolone antibiotics, levothyroxine, and bisphosphonates, as well as iron, magnesium and zinc supplements. Vitamin D in usual doses has no relevant interactions.[2]

    References

    1. 1 2 Multum Consumer Information on calcium and vitamin D combinations.
    2. 1 2 3 Haberfeld, H, ed. (2015). Austria-Codex (in German). Vienna: Österreichischer Apothekerverlag. Cal-D-Vita-Kautabletten.
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