Ananain

Ananain
Identifiers
EC number 3.4.22.31
CAS number 119129-70-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Ananain (EC 3.4.22.31, stem bromelain, fruit bromelain) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with broad specificity for peptide bonds. Best reported small molecule substrate Bz-Phe-Val-Arg-NHMec

This enzyme is isolated from stem of pineapple plant, Ananas comosus.

References

  1. Rowan, A.D.; Buttle, D.J.; Barrett, A.J. (1988). "Ananain: a novel cysteine proteinase found in pineapple stem". Arch. Biochem. Biophys. 267: 262–270. doi:10.1016/0003-9861(88)90031-8. PMID 3196029.
  2. Rowan, A.D.; Buttle, D.J.; Barrett, A.J. (1990). "The cysteine proteinases of the pineapple plant". Biochem. J. 266: 869–875. PMC 1131219. PMID 2327970.
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