23S rRNA (guanine2069-N7)-methyltransferase

23S rRNA (guanine2069-N7)-methyltransferase
Identifiers
EC number 2.1.1.264
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

23S rRNA (guanine2069-N7)-methyltransferase (EC 2.1.1.264, rlmK (gene), 23S rRNA m7G2069 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine2069-N7)-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + guanine2069 in 23S rRNA S-adenosyl-L-homocysteine + N7-methylguanine2069 in 23S rRNA

The enzyme specifically methylates guanine2069 at position N7 in 23S rRNA.

References

  1. Kimura, S.; Ikeuchi, Y.; Kitahara, K.; Sakaguchi, Y.; Suzuki, T.; Suzuki, T. (2012). "Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity". Nucleic Acids Res. 40: 4071–4085. doi:10.1093/nar/gkr1287. PMC 3351187. PMID 22210896.
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