WNT8A

WNT8A
Identifiers
Aliases	WNT8A, WNT8D, Wnt family member 8A
External IDs	OMIM: 606360 MGI: 107924 HomoloGene: 7553 GeneCards: WNT8A
Gene location (Human)
Chr.	Chromosome 5 (human)[1]
End	138,092,365 bp[1]
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)[2]
End	34,548,273 bp[2]
Gene ontology
Molecular function	• receptor binding; • GO:0005110 frizzled binding; • receptor ligand activity;
Cellular component	• extracellular region; • extracellular; • extracellular matrix; • collagen-containing extracellular matrix;
Biological process	• canonical Wnt signaling pathway involved in neural crest cell differentiation; • regulation of transcription involved in anterior/posterior axis specification; • multicellular organism development; • response to retinoic acid; • neural crest cell fate commitment; • neuron differentiation; • canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment; • beta-catenin destruction complex disassembly; • Wnt signaling pathway; • canonical Wnt signaling pathway; • regulation of receptor activity; • secondary palate development; • cell fate commitment;
	Sources:Amigo / QuickGO
Orthologs
	7478
	20890
	ENSG00000061492
	ENSMUSG00000012282
	Q9H1J5
	Q64527
	NM_001300938; NM_001300939; NM_031933; NM_058244
	NM_009290
	NP_001287867; NP_001287868; NP_490645
	NP_033316
	Wikidata
View/Edit Human	View/Edit Mouse

Protein Wnt-8a is a protein that in humans is encoded by the WNT8A gene.[5] Wnt8a may be involved in development of early embryos as well as germ cell tumors.[5]

References

GRCh38: Ensembl release 89: ENSG00000061492 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000012282 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Wnt8a wingless-type MMTV integration site family, member 8A".

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000061492 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000012282 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Wnt8a wingless-type MMTV integration site family, member 8A".

Signaling pathway: Wnt signaling pathway
Ligand	WNT1 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B WNT10A WNT10B WNT11 WNT16
Receptor	Frizzled LRP5 LRP6
Second messenger	Dishevelled GSK-3 APC Beta-catenin