Peginterferon beta-1a

Peginterferon beta-1a', sold under the brand name Plegridy, is medication used to treat multiple sclerosis.

Peginterferon beta-1a
Clinical data
Trade namesPlegridy, Plegridy Pen
AHFS/Drugs.comMonograph
MedlinePlusa614059
License data
Pregnancy
category
  • AU: D [1]
  • US: C (Risk not ruled out) [1]
    Routes of
    administration    		Subcutaneous injection
    Drug classAntineoplastic agent
    ATC code
    Legal status
    Legal status
    • US: ℞-only
    • In general: ℞ (Prescription only)
    Identifiers
    CAS Number
    DrugBank
    UNII
    KEGG
    Chemical and physical data
    FormulaC913H1417N246O256PS7 [C2H4O]n
    Molar mass44000

    The most common side effects include headache, muscle pain, joint pain, influenza (flu)-like symptoms, pyrexia (fever), chills, asthenia (weakness), and erythema (reddening of the skin), pain or pruritus (itching) at the injection site.[2][3]

    Peginterferon beta-1a was approved for medical use in the United Stated and in the European Union in 2014.[4][2]

    Medical uses

    In the United States peginterferon beta-1a is indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.[3]

    In the European Union peginterferon beta-1a is indicated for the treatment of relapsing remitting multiple sclerosis in adults.[2]

    References
    1. "Peginterferon beta-1a (Plegridy) Use During Pregnancy". Drugs.com. 22 July 2019. Retrieved 25 June 2020.
    2. "Plegridy EPAR". European Medicines Agency (EMA). Retrieved 24 June 2020. This article incorporates text from this source, which is in the public domain.
    3. "Plegridy- peginterferon beta-1a kit Plegridy Pen- peginterferon beta-1a kit Plegridy- peginterferon beta-1a injection, solution". DailyMed. 30 March 2020. Retrieved 25 June 2020.
    4. "Drug Approval Package: Plegridy (peginterferon beta-1a) prefilled syringe and Plegridy Pen (peginterferon beta-1a) prefilled pen NDA #125499". U.S. Food and Drug Administration (FDA). 17 September 2014. Retrieved 25 June 2020.


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