Martha Connors

The character was created by Stan Lee and Steve Ditko and first appeared in The Amazing Spider-Man #6 (November 1963).

Sometime before her first appearance, Martha met and married surgeon and biologist Curt Connors. Together they had a son named Billy and their life seemed perfect. However, Curt, an amputee, was looking for a way to regrow lost limbs. Despite Martha's worrying for her husband's safety, Curt had transformed into a terrible lizard monster. Martha managed to meet up with Spider-Man who had encountered the Lizard already and she told her story to the wall-crawler prompting him to successfully cure Curt, albeit temporarily.[1]

During a major story arc, Martha and Billy were kidnapped by the Maggia branch led by Silvermane who wanted Curt to decipher an ancient tablet. Once again, Curt transformed into the Lizard and it took the combined effort Spider-Man and Human Torch save Martha and Billy who were happily reunited with a cured Curt. Curt would continue to transform into the Lizard, but each time Martha would stick by her husband.[2]

Sometime later, Curt mentions that Martha contracted cancer and had died due to the complications of her surgery.[3]

In a lead-up to the Dead No More: The Clone Conspiracy storyline, Martha was revived by Miles Warren, along with Billy who had also died, so that Curt could have a reason to work for him. Martha still works at New U Technologies.[4][5] When New U Technologies suddenly breaks out in a melee, Martha and Billy are taken away by Curt who claims that he can cure their Carrion Virus.[6] Martha and Billy are injected with the lizard formula saving their lives, but now making them lizard-human hybrids.[7]

• Martha Connors at Marvel Wiki