Ethinylestradiol/levonorgestrel

Ethinylestradiol/levonorgestrel (also ethinyl estradiol/levonorgestrel) is a combined birth control pill made up of ethinylestradiol, an estrogen and levonorgestrel a progestin.[2] It is used for birth control, symptoms of menstruation, endometriosis, and as emergency contraception.[1][2] It is taken by mouth.[1]

Ethinylestradiol/levonorgestrel
Combination of
EthinylestradiolEstrogen
LevonorgestrelProgestogen
Clinical data
Trade namesAltavera, Alysena, Amethyst, others[1]
AHFS/Drugs.comMonograph
MedlinePlusa601050
Pregnancy
category
  • US: X (Contraindicated)
    Routes of
    administration
    By mouth
    ATC code
    Legal status
    Legal status

    Side effects can include nausea, headache, blood clots, breast pain, depression, and liver problems.[2] Use is not recommended during pregnancy, the initial three weeks after childbirth, and in those at high risk of blood clots.[2] However, it may be started immediately after a miscarriage or abortion.[3] Smoking while using combined birth control pills is not recommended.[1] It works by stopping ovulation, making the mucus at the opening to the cervix thick, and making the uterus not suitable for implantation.[1]

    Ethinylestradiol/levonorgestrel has been approved for medical use in the United States at least since 1982.[1] It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.[4] It is available as a generic medication.[5] In the United Kingdom three months of medication costs the NHS about 1.80 pounds.[6] In the United States it costs about $25–50 per month.[5] It is marketed under a large number of brand names.[1] In 2017, it was the 136th most commonly prescribed medication in the United States, with more than four million prescriptions.[7][8]

    See also

    References

    1. "Ethinyl estradiol and levonorgestrel medical facts from Drugs.com". www.drugs.com. Archived from the original on 1 January 2017. Retrieved 1 January 2017.
    2. World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 363–5. hdl:10665/44053. ISBN 9789241547659.
    3. "Erlibelle 30micrograms/150micrograms film-coated tablets - Summary of Product Characteristics (SPC) - (eMC)". www.medicines.org.uk. Archived from the original on 2 January 2017. Retrieved 1 January 2017.
    4. World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
    5. Hamilton, Richart (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 349. ISBN 9781284057560.
    6. British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. p. 552. ISBN 9780857111562.
    7. "The Top 300 of 2020". ClinCalc. Retrieved 11 April 2020.
    8. "Ethinyl Estradiol; Levonorgestrel - Drug Usage Statistics". ClinCalc. Retrieved 11 April 2020.
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