CYP27C1

CYP27C1 (cytochrome P450, family 27, subfamily C, polypeptide 1) is a protein that in humans is encoded by the CYP27C1 gene.[3][4]

CYP27C1
Identifiers
AliasesCYP27C1, cytochrome P450 family 27 subfamily C member 1
External IDsHomoloGene: 70240 GeneCards: CYP27C1
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2q14.3Start127,183,832 bp[1]
End127,220,313 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

339761

n/a

Ensembl

ENSG00000186684

n/a

UniProt

Q4G0S4

n/a

RefSeq (mRNA)

NM_001001665
NM_001367501
NM_001367502

n/a

RefSeq (protein)

NP_001001665
NP_001354430
NP_001354431

n/a

Location (UCSC)Chr 2: 127.18 – 127.22 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.[5]

CYP27C1 is the topic of the comic Sherman's lagoon for May 26, 2016.[6] In response to Hawthorne's inquiry about the chemical, Ernest explains that it is an enzyme that enhances ability to see infrared light, allowing fish to see better in murky waters. Ernest can see however that Hawthorne is more interested in how to synthesize it commercially.

References
  1. GRCh38: Ensembl release 89: ENSG00000186684 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. Ota T, Suzuki Y, Nishikawa T, et al. (January 2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  4. Gerhard DS, Wagner L, Feingold EA, et al. (October 2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  5. "Entrez Gene: CYP39A1".
  6. Jim Toomey (May 26, 2016). "Sherman's lagoon".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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