Alpha-humulene 10-hydroxylase
Alpha-humulene 10-hydroxylase (EC 1.14.13.150, CYP71BA1) is an enzyme with systematic name alpha-humulene,NADPH:oxygen 10-oxidoreductase.[1] This enzyme catalyses the following chemical reaction
- alpha-humulene + O2 + NADPH + H+ 10-hydroxy-alpha-humulene + NADP+ + H2O
| Alpha-humulene 10-hydroxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.14.13.150 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Alpha-humulene 10-hydroxylase requires cytochrome P-450.
References
- Yu F, Okamoto S, Harada H, Yamasaki K, Misawa N, Utsumi R (March 2011). "Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis". Cellular and Molecular Life Sciences. 68 (6): 1033–40. doi:10.1007/s00018-010-0506-4. PMID 20730551.
External links
- Alpha-humulene+10-hydroxylase at the US National Library of Medicine Medical Subject Headings (MeSH)
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