Zerumbone synthase

Zerumbone synthase
Identifiers
EC number 1.1.1.326
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Zerumbone synthase (EC 1.1.1.326, ZSD1) is an enzyme with systematic name 10-hydroxy-alpha-humulene:NAD+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

10-hydroxy-alpha-humulene + NAD+ zerumbone + NADH + H+

The enzyme was cloned from shampoo ginger, Zingiber zerumbet.

References

  1. Okamoto, S.; Yu, F.; Harada, H.; Okajima, T.; Hattan, J.; Misawa, N.; Utsumi, R. (2011). "A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet". FEBS J. 278 (16): 2892–2900. doi:10.1111/j.1742-4658.2011.08211.x. PMID 21668645.
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