Trehalose-phosphatase

trehalose-phosphatase
Identifiers
EC number 3.1.3.12
CAS number 9025-72-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a trehalose-phosphatase (EC 3.1.3.12) is an enzyme that catalyzes the chemical reaction

alpha,alpha-trehalose 6-phosphate + H2O alpha,alpha-trehalose + phosphate

Thus, the two substrates of this enzyme are alpha,alpha'-trehalose 6-phosphate and H2O, whereas its two products are alpha,alpha-trehalose and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is alpha,alpha-trehalose-6-phosphate phosphohydrolase. Other names in common use include trehalose 6-phosphatase, trehalose 6-phosphate phosphatase, and trehalose-6-phosphate phosphohydrolase. This enzyme participates in starch and sucrose metabolism.

References

    • CABIB E, LELOIR LF (1958). "The biosynthesis of trehalose phosphate". J. Biol. Chem. 231 (1): 259&ndash, 75. PMID 13538966.
    • CANDY DJ, KILBY BA (1961). "The biosynthesis of trehalose in the locust fat body". Biochem. J. 78: 531&ndash, 6. PMC 1205371. PMID 13690400.


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