TRNASer (uridine44-2'-O)-methyltransferase
| TRNASer (uridine44-2'-O)-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.211 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
TRNASer (uridine44-2'-O)-methyltransferase (EC 2.1.1.211, TRM44) is an enzyme with systematic name S-adenosyl-L-methionine:tRNASer (uridine44-2'-O)-methyltransferase.[1] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + uridine44 in tRNASer S-adenosyl-L-homocysteine + 2'-O-methyluridine44 in tRNASer
The 2'-O-methylation of uridine44 contributes to stability of tRNASer(CGA).
References
- ↑ Kotelawala, L.; Grayhack, E.J.; Phizicky, E.M. (2008). "Identification of yeast tRNA Um44 2′-O-methyltransferase (Trm44) and demonstration of a Trm44 role in sustaining levels of specific tRNASer species". RNA. 14: 158–169. doi:10.1261/rna.811008. PMC 2151035. PMID 18025252.
External links
- TRNASer+(uridine44-2'-O)-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
This article is issued from
Wikipedia.
The text is licensed under Creative Commons - Attribution - Sharealike.
Additional terms may apply for the media files.