Nucleoside oxidase (H2O2-forming)

Nucleoside oxidase
(H2O2-forming)
Identifiers
EC number 1.1.3.39
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Nucleoside oxidase (H2O2-forming) (EC 1.1.3.39) is an enzyme with systematic name nucleoside:oxygen 5'-oxidoreductase (H2O2-forming).[1] This enzyme catalyses the following chemical reaction

adenosine + 2 O2 + H2O 9-riburonosyladenine + 2 H2O2 (overall reaction)
(1a) adenosine + O2 5'-dehydroadenosine + H2O2
(1b) 5'-dehydroadenosine + O2 + H2O 9-riburonosyladenine + H2O2

This enzyme contains Heme and belongs to a flavoprotein family.

References

  1. ↑ Koga, S.; Ogawa, J.; Cheng, L.Y.; Choi, Y.M.; Yamada, H.; Shimizu, S. (1997). "Nucleoside oxidase, a hydrogen peroxide-forming oxidase, from Flavobacterium meningosepticum". Appl. Environ. Microbiol. 63 (11): 4282–4286. PMC 1389282. PMID 16535726.
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