Limone sul Garda

Limone sul Garda
Limù
Comune
Comune di Limone sul Garda
Limone sul Garda
Limone sul Garda
Location of Limone sul Garda in Italy
Coordinates: 45°48′30″N 10°47′15″E / 45.80833°N 10.78750°E / 45.80833; 10.78750Coordinates: 45°48′30″N 10°47′15″E / 45.80833°N 10.78750°E / 45.80833; 10.78750[1]
Country Italy
Region Lombardy
Province Brescia (BS)
Government
 • Mayor Franceschino Risatti
Area
 • Total 26 km2 (10 sq mi)
Elevation 69 m (226 ft)
Population (2011)[2]
 • Total 1,177
 • Density 45/km2 (120/sq mi)
Demonym(s) Limonesi
Time zone UTC+1 (CET)
 • Summer (DST) UTC+2 (CEST)
Postal code 25010
Dialing code 0365
Saint day July 10
Website Official website

Limone sul Garda (Gardesano: Limù) is a town and comune in the province of Brescia, in Lombardy (northern Italy), on the shore of Lake Garda.

History

Despite the presence of famous cultivations of lemons (the meaning of the city's name in Italian), the town's name is probably derived from the ancient lemos (elm) or limes (Latin: boundary, referring to the communes of Brescia and the Bishopric of Trento). In 1863-1905 the denomination was Limone San Giovanni.

Until the 1940s the city was reachable only by lake or through the mountains, with the road to Riva del Garda being built only 1932, but today Limone is one of the most renowned tourist resorts in the area.

Health

In 1979 researchers discovered that people in Limone possess a mutant form of apolipoprotein (called ApoA-1 Milano) in their blood, that induced a healthy form of high-density cholesterol, which resulted in a lowered risk of atherosclerosis and other cardiovascular diseases.[3]

The protein appears to have given residents of the village extreme longevity - a dozen of those living here are over the age of 100 (for c. 1,000 total inhabitants). The origin of the mutation has been traced back to a couple who lived in Limone in the 17th century.[4] Research has been ongoing to develop pharmaceutical treatments against heart disease based on mimicking the beneficial effects of the ApoA-1 mutation.[5]

Sources

  1. ↑ "The World Gazetteer". Archived from the original on 2013-02-09. Retrieved 2007-02-22.
  2. ↑ "ISTAT". demo.istat.it. Archived from the original on 3 March 2016. Retrieved 30 September 2016.
  3. ↑ Sirtori, C. R.; Calabresi, L.; Franceschini, G.; Baldassarre, D.; Amato, M.; Johansson, J.; Salvetti, M.; Monteduro, C.; Zulli, R.; Muiesan, M. L.; Agabiti-Rosei, E. (17 April 2001). "Cardiovascular status of carriers of the apolipoprotein A-I(Milano) mutant: the Limone sul Garda study" (PDF). Circulation. 103 (15): 1949–1954. doi:10.1161/01.cir.103.15.1949. PMID 11306522.
  4. ↑ "LONG LIFE IN LIMONE - Visit Limone Sul Garda". Visit Limone Sul Garda. Retrieved 17 August 2017.
  5. ↑ Lowe, Derek (16 November 2016). "The Long Saga of Apo-A1 Milano". In the Pipeline. Retrieved 17 August 2017.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.