Inclacumab

Inclacumab
Monoclonal antibody
Type	Whole antibody
Source	Human
Target	selectin P
Clinical data
Synonyms	LC1004-002
ATC code	none
Identifiers
CAS Number	1256258-86-2
ChemSpider	none
KEGG	D10356
Chemical and physical data
Formula	C₆₄₅₂H₉₉₃₀N₁₇₃₀O₂₀₂₄S₄₂
Molar mass	145.5 kDa

Inclacumab (LC1004-002) (INN) is a human monoclonal antibody designed for the treatment of cardiovascular disease.^[1]^[2]

This drug was developed by Genentech/Roche.

References

↑ World Health Organization (2011). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 106" (PDF). WHO Drug Information. 25 (4).
↑ Statement On A Nonproprietary Name Adopted By The USAN Council - Inclacumab, American Medical Association.

Monoclonals for bone, musculoskeletal, circulatory, and neurologic systems

Bone ("-os-", "-s(o)-")

Human ("-osu-")	Burosumab Denosumab
Humanized ("-sozu-")	Blosozumab Romosozumab

Musculoskeletal ("-mul-")

Human ("-mulu-")	Stamulumab^†

Circulatory ("-c(i[r])-")

Human ("-ciru-")	Alirocumab Ascrinvacumab Enoticumab Evinacumab^† Evolocumab Icrucumab Inclacumab Nesvacumab Orticumab Ramucirumab Rinucumab Vesencumab
Mouse ("-ciro-")	Biciromab^‡ Imciromab^‡
Chimeric ("-cixi-")	Abciximab Volociximab
Humanized ("-cizu-")	Alacizumab pegol Bevacizumab/Ranibizumab Bococizumab Brolucizumab^† Caplacizumab Demcizumab Etaracizumab Faricimab^† Idarucizumab Ralpancizumab Tadocizumab Vanucizumab

Neurologic ("-ne(u)(r)-")

Human ("-neru-")	Aducanumab^† Atinumab Elezanumab Erenumab^† Fasinumab^† Fulranumab Gantenerumab^† Opicinumab
Humanized ("-nezu-"/"-neuzu-")	Bapineuzumab^† Crenezumab^† Eptinezumab^† Fremanezumab^† Galcanezumab Ozanezumab Ponezumab Refanezumab Solanezumab Tanezumab^†
Veterinary ("-nevet-")	Frunevetmab Ranevetmab

Angiogenesis inhibitor ("-anibi-")

Humanized ("-anibizu-")	Ranibizumab

Growth factor ("-gr(o)-")

Human ("-gru-")	Bimagrumab Trevogrumab
Humanized ("-grozu-")	Domagrozumab Landogrozumab

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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