Hydrocortisone aceponate

Hydrocortisone aceponate
Clinical data
AHFS/Drugs.com	Monograph
Routes of; administration	Topical
ATC code	D07AC16 (WHO) ;
Identifiers
	IUPAC name (11β)-21-(acetyloxy)-11-hydroxy-3,20-dioxopregn-4-en-17-yl propionate;
CAS Number	74050-20-7 ;
PubChem CID	68921;
ChemSpider	62148 ;
UNII	2340UP1L2G;
KEGG	D06876 ;
ChEMBL	CHEMBL2106309 ;
ECHA InfoCard	100.184.885
Chemical and physical data
Formula	C26H36O7
Molar mass	460.560 g/mol
3D model (JSmol)	Interactive image;
	SMILES CCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)C(=O)COC(=O)C;
	InChI InChI=1S/C26H36O7/c1-5-22(31)33-26(21(30)14-32-15(2)27)11-9-19-18-7-6-16-12-17(28)8-10-24(16,3)23(18)20(29)13-25(19,26)4/h12,18-20,23,29H,5-11,13-14H2,1-4H3/t18-,19-,20-,23+,24-,25-,26-/m0/s1 ; Key:MFBMYAOAMQLLPK-FZNHGJLXSA-N ;
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Hydrocortisone aceponate is a corticosteroid that is used in form of creams for the treatment of various dermatoses (skin conditions).^[1] It is an ester of hydrocortisone (cortisol) with acetic acid and propionic acid.

References

↑ Baghel, V.; Mukhopadhyay, A. (2010). "A study to evaluate the efficacy and safety of hydrocortisone aceponate 0.127% lipophilic cream in steroid responsive dermatoses in Indian patients". Indian Journal of Dermatology, Venereology and Leprology. 76 (5): 591. doi:10.4103/0378-6323.69093. PMID 20827017.

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Clinical data

AHFS/Drugs.com	Monograph
Routes of administration	Topical
ATC code	D07AC16 (WHO)
Identifiers
IUPAC name (11β)-21-(acetyloxy)-11-hydroxy-3,20-dioxopregn-4-en-17-yl propionate
CAS Number	74050-20-7^Y
PubChem CID	68921
ChemSpider	62148^N
UNII	2340UP1L2G
KEGG	D06876^Y
ChEMBL	CHEMBL2106309^N
ECHA InfoCard	100.184.885
Chemical and physical data
Formula	C₂₆H₃₆O₇
Molar mass	460.560 g/mol
3D model (JSmol)	Interactive image
SMILES CCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)C(=O)COC(=O)C
InChI InChI=1S/C26H36O7/c1-5-22(31)33-26(21(30)14-32-15(2)27)11-9-19-18-7-6-16-12-17(28)8-10-24(16,3)23(18)20(29)13-25(19,26)4/h12,18-20,23,29H,5-11,13-14H2,1-4H3/t18-,19-,20-,23+,24-,25-,26-/m0/s1^N Key:MFBMYAOAMQLLPK-FZNHGJLXSA-N^N
^NY (what is this?) (verify)